Rick and Morty is a brilliant show with some very intelligent minds behind it, and when it comes to storytelling these beautifully twisted minds don't miss a beat.
Aside from intelligently geeky writing they've also made an unwavering commitment to preserve continuity, so those fans who have watched every episode can get some extra laughs out of those "inside" jokes.
Ever notice that Rick never wears a seat belt? That actually symbolizes more than you think (SPOILERS):
You can see it almost every time the two of them get into a vehicles -- Morty straps into a seatbelt, while Rick remains unrestrained. It's a small detail, but one that's been consistent throughout the show's three seasons, no matter who's in the cockpit and who's driving.
The show doesn't slip up. When Rick does wear a seatbelt, it's for a reason.
In season three's "Rest and Ricklaxation," Rick is split into two distinct personalities. All of what Rick would be considered to be "toxic" aspects of himself are sent to a boogery hellworld, where the rottenness congeals into Toxic Rick. Meanwhile, Clean Rick and Clean Morty are left behind to have pleasant if slightly off-center adventures. Since the "toxic" parts of Rick are no longer present, Clean Rick puts on his seatbelt. This is a Rick that has something to live for, and has left his death wish behind.
Rick is only seen wearing a seatbelt in his normal state one time: Just after he transforms back from Pickle Rick.
This is significant because it takes place not long after Rick has a breakthrough in family therapy. Up until that moment, he had avoided the scheduled session by turning himself into a pickle (it really helps if you're caught up on the show). After facing his personal demons head-on, Rick becomes resigned to the idea that he should probably look after himself if he's going to look after his family.
See 10 Times Rick and Morty Paid Incredible Attention to Continuity here