The name of the video is The Poop in My Pants, but don't let that preventing you from watching, it's SFW. The Rick and Morty character Mr. Poopybutthole is going over the events in his life and all the things he has to be thankful for.
You don't have to be a Rick and Morty fan, or even watch the show at all, to find this video from Adult Swim charming. However, if you do watch it, you'll see a lot of references to season three of the show. -via Uproxx