Johnny Depp is one of Hollywood's most recognizable actors, and one of the most popular by far, but back before he had achieved superstar status he was a guitar obsessed teen who couldn't tune in to school- so he dropped out.
He discussed his school days and a certain hotel room incident with Carl Fussman back in 2009, then Quoted Studios cartoonified the interview for their Blank on Blank series. (NSFW language)