Superman has been drunk on power, high on drugs made specifically for Kryptonians and delirious after a spell was cast on his mind, but his alien metabolism makes it virtually impossible for him to get drunk on Earth booze.
But if he's able to get his hands on some Kryptonian Moonjuice or Martian Ripple he transforms into Drunk Superman- with the power to pee on (and piss off) the Batman faster than a speeding bullet.
Australian visual effects artist Darren Wallace created this silly parody video that shows why we Earthlings need to make sure Supes stays sober- because humans are fragile!
-Via comicbook