The eleventh episode in the sixth season of Friends is called "The One with the Apothecary Table." It's 22 minutes long. But YouTube user Tunglebrek removed all of the jokes and almost all of the laugh track so that it's just 2 minutes, 43 seconds long. The plot remains entirely coherent with two clearly discernible story arcs (an A story and a B story).
He's also done similar work with an episode of The Big Bang Theory (1 minute, 28 seconds) and an episode of Seinfeld (3 minutes, 3 seconds). What other shows would you like to see subjected to this treatment?
-via 22 Words