I'm deeply impressed with the ingenuity of Instructables member roggie1994. This drawer fits snugly into its frame. Inside the face of the drawer are steel bolts. They can slide in and out of grooves in the frame. But the only way to easily open or close them is to use magnets to move the bolts through the wood. The handles come off and can be stored separately.
Roggie1994 envisions this design for a secret compartment. It would probably be hidden from casual thieves who didn't know what they were looking at. It's like a wooden safe.