I have no idea what this Star Trek novel is about, but I feel a great compulsion to read it. The title, which probably takes its inspiration from the 2002 movie My Big Fat Greek Wedding, is perfect.
My Big Fat Vulcan Wedding is a fan-written novella set in the time period of the original series. You can read the first few chapters here. From glancing at them, I gather that it is set on an old freighter named Calypso and includes many references to the Enterprise series.