The artist Han Jan presents Rainbow Dash as Thor, Spike as the Hulk, Fluttershy as War Machine, Pinkie Pie as Iron Man, Applejack as Captain America, Rarity as Black Widow and Twilight Sparkle as Nick Fury. The last pairing is particularly apt because the black outfit and eye patch match Twilight Sparkle's appearance in the time travel episode "It's about Time."
Does Han Jan's style look familiar? We've previously featured his array of Gundam ponies.