Italian artist Giuseppe Veneziano updated the Greek myth of Perseus and Medusa with this sculpture. It's a bit harsh. I mean, Ronald McDonald never turned anyone into stone.
Artist's Website (some NSFW images) -via Kurositas | Photo by Flickr user mamasaurus rex used under Creative Commons license
UPDATE: In the comments, Sylvian proposes that this sculpture is actually a take on Caravaggio's David with the Head of Goliath. I think he's right.
Interestingly enough, the statue of David by Michelangelo, was put in front of the courthouse in Florence back in the 1500s, to represent the little guys of Florence against the giant powers, the Medicis.