Leave it to Mad Magazine to craft a rejection letter that doesn't leave you feel too rejected:
There's nothing like a helping of light-hearted humour to ease the pain of rejection, as evidenced by this form letter from the offices of Mad magazine, one of the most influential humour publications ever released. The letter was sent to all unsuccessful submitters of material during the much-lauded reign of Al Feldstein.
From the always awesome Letters of Note - via Nerdcore