Morris (a.k.a. Internet Worm) - November 1988
This computer virus infected over 6,000 computer systems in the United States, including the famous NASA research Institute, which for some time remained completely paralyzed. Due to erratic code, the worm managed to send millions of copies of itself to different network computers, being able to entirely paralyze all network resources. The damages caused by the Morris computer virus were estimated at $96 millions.
To be able to spread the computer virus used errors in such operating systems as Unix for VAX and Sun Microsystems. There were a number of other interesting ideas used by the virus - for example it could pick user passwords.
From the Upcoming ueue, submitted by coconutnut.
And perhaps the lamest comment section ever.
That's easy!
Microsoft Windows