(YouTube Link)
This video is about a man who lives with First-Person Shooter Disease (AKA Duke Nukem's Disease) -- he can only interact with the world in the manner of a video game character. Yet he bravely struggles on to overcome obstacles of hand-eye coordination and peripheral vision.
Via Geekologie
"uh..i can't"
Hilarious.
This is one of those two second jokes that someone felt they could flog into a five-minute joke. Sadly, they failed.