Tanya suffers from a rare condition called acromegaly, where excessive amounts of growth hormone are released. Andre the Giant was a famous sufferer, as was Richard Keil who portrayed the famous villain "Jaws" in the James Bond movies.
In Tanya's case, a tumor wrapped itself around her pituitary gland, causing her condition. Unfortunately, despite several surgeries and medication, it has failed to stop the release of growth hormone. Today Tanya is a staggering 6'6" (2.0 m) and 480 pounds (218 kg), and still growing.
From the Upcoming ueue, submitted by Geekazoid.