Canadian poet Christian Bök wants his work to live on after he’s gone. Like, billions of years after. He’s going to encode it directly into the DNA of the hardy bacteria Deinococcus radiodurans. If it works, his poem could outlast the human race. But it’s a tricky procedure, and Bök is doing what he can to make it even trickier. He wants to inject the DNA with a string of nucleotides that form a comprehensible poem, and he also wants the protein that the cell produces in response to form a second comprehensible poem.[...]
Bök will create a code that links letters of the alphabet with genetic nucleotides (adenine, cytosine, guanine, and thymine, aka ACGT). Each triplet of nucleotides will correspond to a letter so that, say, ACT represents the letter a, AGT represents the letter b, and so on.
Link via Marginal Revolution | Image: US Department of Energy
In addition, bacterias are prokaryotes, which means they have a higher mutation rate anyway (their DNA istn't tucked safely away in a cell core).
But then again: It's art, it doesn't have to work.